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TitleD-Cycloserine Inactivation of D-Amino Acid Aminotransferase Leads to a Stable Noncovalent Protein Complex with an Aromatic Cycloserine-Plp Derivative
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 120, Page 2268-2274, Year 1998
Publish dateOct 27, 1997 (structure data deposition date)
AuthorsPeisach, D. / Chipman, D.M. / Van Ophem, P.W. / Manning, J.M. / Petsko, G.A. / Ringe, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2daa:
CRYSTALLOGRAPHIC STRUCTURE OF D-AMINO ACID AMINOTRANSFERASE INACTIVATED BY D-CYCLOSERINE
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-DCS:
D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE

ChemComp-HOH:
WATER

Source
  • bacillus sp. (bacteria)
KeywordsPYRIDOXAL PHOSPHATE / PYRIDOXAMINE / TRANSAMINASE / ANTIBIOTIC / SUICIDE SUBSTRATE / CYCLOSERINE / TRANSFERASE / AMINOTRANSFERASE

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