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TitleThe Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine
Journal, issue, pagesTo be Published
Publish dateFeb 1, 2010 (structure data deposition date)
AuthorsBateman, K.S. / Cherney, M.M. / Withers, S.G. / Mahuran, D.J. / Tropak, M. / James, M.N.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3lmy:
The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NDG:
2-acetamido-2-deoxy-alpha-D-glucopyranose

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CP6:
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / 6-stranded anti-parallel beta-sheet / TIM barrel / Disease mutation / Disulfide bond / Gangliosidosis / Glycoprotein / Glycosidase / Lysosome

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