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TitleDeciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N-C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis
Journal, issue, pagesAcs Catalysis, Vol. 12, Page 2270-2279, Year 2022
Publish dateSep 28, 2021 (structure data deposition date)
AuthorsChen, T.Y. / Zheng, Z. / Zhang, X. / Chen, J. / Cha, L. / Tang, Y. / Guo, Y. / Zhou, J. / Wang, B. / Liu, H.W. / Chang, W.C.
External linksAcs Catalysis / Search PubMed
MethodsX-ray diffraction
Resolution1.99 Å
Structure data

PDB-7scp:
The crystal structure of ScoE in complex with intermediate
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

Chemicals

ChemComp-FE2:
Unknown entry

ChemComp-8S6:
(3R)-3-(oxaloamino)butanoic acid

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • streptomyces coeruleorubidus (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Iron/2-oxoglutarate dependent / Fe/2OG / isonitrile biosynthesis

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