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TitleTargeting PWWP domain of DNMT3B for epigenetic cancer therapy: identification and structural characterization of potential protein-protein interaction inhibitors
Journal, issue, pagesTo be published
Publish dateMar 20, 2019 (structure data deposition date)
AuthorsRondelet, G. / Dal Maso, T. / Maniquet, A. / Themans, Q. / Wouters, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.269 Å
Structure data

PDB-6r3e:
Human DNMT3B PWWP domain in complex with triisopropanolamine
Method: X-RAY DIFFRACTION / Resolution: 2.269 Å

Chemicals

ChemComp-96H:
Triisopropanolamine

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / DNMT3B PWWP DOMAIN / HISTONE BINDING / BETA BARREL / LIGAND

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