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TitleCrystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Mivebresib ABBV-075
Journal, issue, pagesTo Be Published
Publish dateOct 16, 2025 (structure data deposition date)
AuthorsJwala, N. / Chandrasekhar, A. / NarasimhaRao, K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-9x7c:
Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Mivebresib ABBV-075
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-8NG:
N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / BRD2 / Cancer Ligand bound / Inhbitor

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