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TitleBinding of Mg2+ATP Enhances Inhibition of Human Mitochondrial Tryptophanyl-tRNA Synthetase by Indolmycin
Journal, issue, pagesTo Be Published
Publish dateNov 3, 2015 (structure data deposition date)
AuthorsWilliams, T.L. / Carter Jr., C.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.82 Å
Structure data

PDB-5ekd:
Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

Chemicals

ChemComp-5BX:
(5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE/ANTIBIOTIC / TrpRS / indolmycin / mitochondrial / complex / LIGASE-ANTIBIOTIC complex

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