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Author
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Structure paper

TitleActivity and fidelity of human DNA polymerase alpha depend on primer structure
Journal, issue, pagesJ. Biol. Chem., Year 2018
Publish dateMay 12, 2014 (structure data deposition date)
AuthorsBaranovskiy, A.G. / Duong, V. / Babayeva, N.D. / Zhang, Y. / Pavlov, Y. / Anderson, K. / Tahirov, T.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-4qcl:
Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-DCP:
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA/RNA / B-FAMILY DNA POLYMERASE / DNA REPLICATION / TRANSFERASE-DNA-RNA COMPLEX

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