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TitleNovel Fis1 inhibiting peptide reverses microvascular endothelial dysfunction in vessels from humans with type 2 diabetes
Journal, issue, pagesTo Be Published
Publish dateSep 4, 2023 (structure data deposition date)
AuthorsNolden, K.A. / Kakarla, M. / Egner, J.M. / Wang, J. / Harwig, M.C. / Puppala, V.K. / Hofeld, B.C. / Arnold, L.A. / Trykall, D.Z. / Peterson, F.C. ...Nolden, K.A. / Kakarla, M. / Egner, J.M. / Wang, J. / Harwig, M.C. / Puppala, V.K. / Hofeld, B.C. / Arnold, L.A. / Trykall, D.Z. / Peterson, F.C. / Roberts, M.L. / Jenson, D.M. / Hill, R.B. / Widlansky, M.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-8u1z:
Crystal structure of the Fis1 cytosolic domain bound to a peptide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPEPTIDE BINDING PROTEIN/INHIBITOR / tetracopipeptide repeat protein / mitochondria / inhibitor / fission / PEPTIDE BINDING PROTEIN-INHIBITOR complex

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