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Structure paper

TitleExploring an alternative antibody interaction mechanism
Journal, issue, pagesTo be Published
Publish dateNov 19, 2012 (structure data deposition date)
AuthorsOyen, D. / Steyaert, J. / Barlow, J.N.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.6 - 1.888 Å
Structure data

PDB-4i13:
Nanobody ca1697 binding to the DHFR.folate binary complex
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4i1n:
R104A-ca1697 nanobody binding to the binary DHFR.folate complex
Method: X-RAY DIFFRACTION / Resolution: 1.888 Å

Chemicals

ChemComp-FOL:
FOLIC ACID

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • lama glama (llama)
KeywordsOXIDOREDUCTASE/IMMUNE SYSTEM / alpha/beta fold / immunoglobulin fold / reductase / NADPH / folate derivatives / reduction / OXIDOREDUCTASE-IMMUNE SYSTEM complex / hydride transfer

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