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-Structure paper
Title | Discovery of DYR684, a Potent, Selective, Metabolically Stable, DYRK1A/B PROTAC utilizing a Novel Cereblon Molecular Glue |
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Journal, issue, pages | To Be Published |
Publish date | Jun 6, 2023 (structure data deposition date) |
Authors | Montfort, W.R. / Basantes, L.E. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.85 Å |
Structure data | PDB-8t2h: |
Chemicals |
ChemComp-XIR: ChemComp-PG4: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | LIGASE/LIGASE INHIBITOR / Kinase / Inhibitor / Alzheimer's Disease / LIGASE / LIGASE-LIGASE INHIBITOR complex |