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TitleStructural basis for the subtype-selectivity of KCa2.2 channel activators.
Journal, issue, pagesTo Be Published
Publish dateSep 5, 2025 (structure data deposition date)
AuthorsNam YW / Zhang M
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.4 - 4.73 Å
Structure data

72519

9y5q

EMDB-72519, PDB-9y5q:
Cryo EM structure of KCa3.1_R355K_I/calmodulin channel in complex with rimtuzalcap
Method: EM (single particle) / Resolution: 4.73 Å

72841

9ydz

EMDB-72841, PDB-9ydz:
Cryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap
Method: EM (single particle) / Resolution: 3.4 Å

Chemicals

ChemComp-K:
Unknown entry

PDB-1b92:
MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Ion channel / Intermediate conductance calcium-activated potassium channel / Calmodulin binding protein

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