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Structure paper

TitleCryo-EM structure of CSN-N8CUL1 in complex with CSN5i-3
Journal, issue, pagesTo Be Published
Publish dateNov 20, 2024 (structure data deposition date)
AuthorsShi H / Zheng N
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.03 Å
Structure data

47981

9efv

EMDB-47981, PDB-9efv:
Cryo-EM structure of CSN-N8CUL1 in complex with CSN5i-3
Method: EM (single particle) / Resolution: 3.03 Å

Chemicals

ChemComp-6LT:
3-(difluoromethyl)-N-{6-[(5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl][1,1'-biphenyl]-3-yl}-1-(propan-2-yl)-1H-pyrazole-5-carboxamide

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / COP9 / COP9 signalosome / signalosome / deneddylation / N8CUL1 / CSN5i-3 / othosteric molecular glue

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