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TitleCrystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
Journal, issue, pagesto be published
Publish dateFeb 22, 2018 (structure data deposition date)
AuthorsDranow, D.M. / Abendroth, J. / Baragana, B. / Walpole, C. / Lorimer, D.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6chd:
Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-KAA:
5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / TRANSFERASE / ATP binding / aminoacylation / amino acid binding / ATP adenylyltransferase activity / tRNA binding / Structure-guided Drug Discovery Consortium

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