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Structure paper

TitleCrystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide
Journal, issue, pagesTo Be Published
Publish dateOct 1, 2018 (structure data deposition date)
AuthorsDranow, D.M. / Conrady, D.G. / Lorimer, D.D. / Horanyi, P.S. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-6mn8:
Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HFG:
7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one / medication*YM

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-2PN:
IMIDODIPHOSPHORIC ACID

ChemComp-GLY:
GLYCINE

ChemComp-SER:
SERINE

ChemComp-HOH:
WATER

Source
  • onchocerca volvulus (invertebrata)
KeywordsLIGASE / SSGCID / ProRS / ATP-binding / aminoacylation / halofuginone / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease

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