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Structure paper

TitleDiscovery and Design of novel Tubulin inhibitors
Journal, issue, pagesTo Be Published
Publish dateJan 12, 2018 (structure data deposition date)
AuthorsZhang, H. / Luo, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5z4p:
Crystal structure of tubulin-stathmin-TTL-Compound TCA complex
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-97O:
6,7,8-trimethoxy-1-(4-methoxyphenyl)-4,5-dihydro-2~{H}-benzo[e]indazole

ChemComp-IMD:
IMIDAZOLE

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
  • rattus norvegicus (Norway rat)
  • gallus gallus (chicken)
KeywordsOXYGEN TRANSPORT / Tubulin

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