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Structure paper

TitleDesign and Synthesis of Tetrahydroquinoxalines as Domain Selective BET Inhibitors
Journal, issue, pagesTo Be Published
Publish dateJan 6, 2018 (structure data deposition date)
AuthorsChung, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-6ffd:
Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-D7T:
1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / INHIBITOR / HISTONE / EPIGENETIC READER / BROMODOMAIN / BRD4 / BROMODOMAIN CONTAINING PROTEIN 4 / ANTAGONIST

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