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TitleCryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric pre-active state
Journal, issue, pagesTo Be Published
Publish dateMay 21, 2024 (structure data deposition date)
AuthorsMihaylov DB / Malinauskas T / Aricescu AR
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.3 Å
Structure data

50346

9fez

EMDB-50346, PDB-9fez:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric bound-closed state
Method: EM (single particle) / Resolution: 3.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HSM:
HISTAMINE

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / GABA / neurotransmission / gating cycle / time-resolved cryo-EM

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