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Structure paper

TitleArchitecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control
Journal, issue, pagesScience, Year 2025
Publish dateSep 23, 2024 (structure data deposition date)
AuthorsGrabarczyk, D. / Ehrmann, J. / Murphy, P. / Yang, W. / Kurzbauer, R. / Bell, L. / Deszcz, L. / Neuhold, J. / Schleiffer, A. / Shulkina, A. ...Grabarczyk, D. / Ehrmann, J. / Murphy, P. / Yang, W. / Kurzbauer, R. / Bell, L. / Deszcz, L. / Neuhold, J. / Schleiffer, A. / Shulkina, A. / Lee, J. / Shin, J. / Meinhart, A. / Versteeg, G. / Zavodszky, E. / Song, H. / Hegde, R. / Clausen, T.
External linksScience / Search PubMed
MethodsX-ray diffraction
Resolution1.71 - 1.92 Å
Structure data

PDB-9jni:
KCMF1 Zn-coordinating domains with RCKG peptide (Sulfonic Cysteine)
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-9upz:
KCMF1 Zn-coordinating domains with RTGG peptide
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPEPTIDE BINDING PROTEIN / Complex / ZZ-domain / C2H2 Zn-finger domain / KCMF1 / Arg/N-degon pathway / LIGASE / Arg/N-degron pathway

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