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TitleCrystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP
Journal, issue, pagesTo be Published
Publish dateMay 19, 2010 (structure data deposition date)
AuthorsLiu, Y. / Kotra, L.P. / Pai, E.F.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-3n34:
Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-FNU:
6-amino-5-fluorouridine 5'-(dihydrogen phosphate)

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsLYASE / P. falciparum / orotidine 5'-monophosphate decarboxylase / 5-fluoro-6-amino-UMP / 5-fluoro-6-azido-UMP

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