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TitleStructural basis of Escherichia coli nitroreductase NfsB triple mutants engineered for improved activity and regioselectivity toward the prodrug CB1954
Journal, issue, pagesPROCESS BIOCHEM, Vol. 50, Page 1760-1766, Year 2015
Publish dateDec 6, 2014 (structure data deposition date)
AuthorsBai, J. / Yang, J. / Zhou, Y. / Yang, Q.
External linksPROCESS BIOCHEM / Search PubMed
MethodsX-ray diffraction
Resolution2.001 Å
Structure data

PDB-3x22:
Crystal structure of Escherichia coli nitroreductase NfsB mutant N71S/F123A/F124W
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-HOH:
WATER

Source
  • escherichia coli k-12 (bacteria)
KeywordsOXIDOREDUCTASE / Nitroreductase / regioselectivity / prodrug activation / CB1954

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