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Structure paper

TitleZincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
Journal, issue, pagesScience, Year 2025
Publish dateDec 2, 2024 (structure data deposition date)
AuthorsBianchi D / Borza R / De Zan E / Huelsz-Prince G / Gregoricchio S / Dekker M / Fish A / Mazouzi A / Kroese L / Linder S ...Bianchi D / Borza R / De Zan E / Huelsz-Prince G / Gregoricchio S / Dekker M / Fish A / Mazouzi A / Kroese L / Linder S / Hernandez Quiles M / Vermeulen M / Celie P / Krimpenfort P / Song J / Zwart W / Wessels L / Nijman S / Perrakis A / Brummelkamp T
External linksScience / Search PubMed
MethodsEM (single particle)
Resolution3.16 - 3.26 Å
Structure data

52226

9hjt

EMDB-52226, PDB-9hjt:
Structure of Zincore (SEPHS1:QRICH1) binding to ZFP91 on DNA
Method: EM (single particle) / Resolution: 3.26 Å

52227

9hju

EMDB-52227, PDB-9hju:
Structure of 2x Zincore (SEPHS1:QRICH1) binding to ZFP91 on DNA
Method: EM (single particle) / Resolution: 3.16 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / Zincore Complex / Transcriptional regulator complex / SEPHS1 / Selenide / water dikinase 1 / selenophosphate synthetase 1 / QRICH1 / Zinc finger protein / ZFP91 / Transcription factor

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