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-Structure paper
Title | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. |
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Journal, issue, pages | Biochemistry, Vol. 38, Page 1087-1094, Year 1999 |
Publish date | Jun 19, 1998 (structure data deposition date) |
![]() | Sotelo-Mundo, R.R. / Ciesla, J. / Dzik, J.M. / Rode, W. / Maley, F. / Maley, G.F. / Hardy, L.W. / Montfort, W.R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.6 - 3.3 Å |
Structure data | ![]() PDB-1rts: ![]() PDB-2tsr: |
Chemicals | ![]() ChemComp-UMP: ![]() ChemComp-D16: ![]() ChemComp-HOH: |
Source |
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![]() | METHYLTRANSFERASE / THYMIDYLATE SYNTHASE / DUMP / TOMUDEX / ANTIFOLATE |