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Structure paper

TitleInhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 95, Page 12956-12960, Year 1998
Publish dateJul 29, 1998 (structure data deposition date)
AuthorsPeterson, S.A. / Klabunde, T. / Lashuel, H.A. / Purkey, H. / Sacchettini, J.C. / Kelly, J.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:9789022
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1bm7:
HUMAN TRANSTHYRETIN (PREALBUMIN) COMPLEX WITH FLUFENAMIC ACID (2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1bmz:
HUMAN TRANSTHYRETIN (PREALBUMIN)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-FLF:
2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID / antiinflammatory, inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / THYROXINE TRANSPORT / HORMONE/GROWTH FACTOR / HORMONE-GROWTH FACTOR COMPLEX

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