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TitleEfficiency of signalling through cytokine receptors depends critically on receptor orientation.
Journal, issue, pagesNature, Vol. 395, Page 511-516, Year 1998
Publish dateMay 25, 1999 (structure data deposition date)
AuthorsSyed, R.S. / Reid, S.W. / Li, C. / Cheetham, J.C. / Aoki, K.H. / Liu, B. / Zhan, H. / Osslund, T.D. / Chirino, A.J. / Zhang, J. ...Syed, R.S. / Reid, S.W. / Li, C. / Cheetham, J.C. / Aoki, K.H. / Liu, B. / Zhan, H. / Osslund, T.D. / Chirino, A.J. / Zhang, J. / Finer-Moore, J. / Elliott, S. / Sitney, K. / Katz, B.A. / Matthews, D.J. / Wendoloski, J.J. / Egrie, J. / Stroud, R.M.
External linksNature / PubMed:9774108
MethodsX-ray diffraction
Resolution1.9 - 2.8 Å
Structure data

PDB-1cn4:
ERYTHROPOIETIN COMPLEXED WITH EXTRACELLULAR DOMAINS OF ERYTHROPOIETIN RECEPTOR
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1eer:
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHEMATOPOIETIC CYTOKINE / CYTOKINE RECEPTOR / COMPLEX (CYTOKINE/RECEPTOR) / ERYTHROPOIETIN / ERYTHROPOIETIN RECEPTOR / SIGNAL TRANSDUCTION / CYTOKINE RECEPTOR CLASS 1 / COMPLEX (CYTOKINE-RECEPTOR) / COMPLEX (CYTOKINE-RECEPTOR) complex

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