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Structure paper

TitleCrystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 95, Page 12562-12567, Year 1998
Publish dateJun 2, 1998 (structure data deposition date)
AuthorsMurali, R. / Sharkey, D.J. / Daiss, J.L. / Murthy, H.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:9770525
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1bgx:
TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • thermus aquaticus (bacteria)
  • mus musculus (house mouse)
KeywordsCOMPLEX (POLYMERASE/INHIBITOR) / DNA POLYMERASE / FAB / PCR / INHIBITION / HELIX-COIL DYNAMICS / INHIBITOR DESIGN / COMPLEX (POLYMERASE-INHIBITOR) / COMPLEX (POLYMERASE-INHIBITOR) complex

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