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Structure paper

TitleVEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Journal, issue, pagesStructure, Vol. 6, Page 1153-1167, Year 1998
Publish dateJun 30, 1998 (structure data deposition date)
AuthorsMuller, Y.A. / Chen, Y. / Christinger, H.W. / Li, B. / Cunningham, B.C. / Lowman, H.B. / de Vos, A.M.
External linksStructure / PubMed:9753694
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-1bj1:
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / COMPLEX (ANTIBODY-ANTIGEN) / ANGIOGENIC FACTOR

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