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TitleStructural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Journal, issue, pagesNature, Vol. 395, Page 237-243, Year 1998
Publish dateJun 22, 1998 (structure data deposition date)
AuthorsRusso, A.A. / Tong, L. / Lee, J.O. / Jeffrey, P.D. / Pavletich, N.P.
External linksNature / PubMed:9751050
MethodsX-ray diffraction
Resolution2.8 - 3.4 Å
Structure data

PDB-1bi7:
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-1bi8:
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Source
  • homo sapiens (human)
KeywordsCOMPLEX (KINASE/ANTI-ONCOGENE) / CYCLIN DEPENDENT KINASE / CYCLIN DEPENDENT KINASE INHIBITORY PROTEIN / CDK / INK4 / CELL CYCLE / MULTIPLE TUMOR SUPPRESSOR / MTS1 / COMPLEX (KINASE-ANTI-ONCOGENE) / COMPLEX (KINASE-ANTI-ONCOGENE) complex / COMPLEX (KINASE/INHIBITOR) / COMPLEX (KINASE-INHIBITOR) / COMPLEX (KINASE-INHIBITOR) complex

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