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Structure paper

TitleLigand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.
Journal, issue, pagesNature, Vol. 395, Page 137-143, Year 1998
Publish dateJul 2, 1998 (structure data deposition date)
AuthorsNolte, R.T. / Wisely, G.B. / Westin, S. / Cobb, J.E. / Lambert, M.H. / Kurokawa, R. / Rosenfeld, M.G. / Willson, T.M. / Glass, C.K. / Milburn, M.V.
External linksNature / PubMed:9744270
MethodsX-ray diffraction
Resolution2.2 - 2.3 Å
Structure data

PDB-1prg:
LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2prg:
LIGAND-BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-BRL:
2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / THIAZOLIDINEDIONE / LIGAND-BINDING DOMAIN / NUCLEAR RECEPTOR / APO / TRANSCRIPTION FACTOR / ORPHAN RECEPTOR / COMPLEX (THIAZOLIDINEDIONE/RECEPTOR) / COMPLEX (THIAZOLIDINEDIONE-RECEPTOR) / COMPLEX (THIAZOLIDINEDIONE-RECEPTOR) complex

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