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TitleCrystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases.
Journal, issue, pagesJ. Mol. Biol., Vol. 282, Page 359-368, Year 1998
Publish dateJun 10, 1998 (structure data deposition date)
AuthorsMaignan, S. / Guilloteau, J.P. / Zhou-Liu, Q. / Clement-Mella, C. / Mikol, V.
External linksJ. Mol. Biol. / PubMed:9735293
MethodsX-ray diffraction
Resolution2 - 2.5 Å
Structure data

PDB-1bhl:
CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1bi4:
CATALYTIC DOMAIN OF HIV-1 INTEGRASE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1bl3:
CATALYTIC DOMAIN OF HIV-1 INTEGRASE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • human immunodeficiency virus 1
KeywordsDNA INTEGRATION / AIDS / POLYPROTEIN / HYDROLASE / ENDONUCLEASE / POLYNUCLEOTIDYL TRANSFERASE / DNA BINDING (VIRAL)

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