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-Structure paper
Title | Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K. |
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Journal, issue, pages | J. Med. Chem., Vol. 41, Page 3563-3567, Year 1998 |
Publish date | Sep 10, 1997 (structure data deposition date) |
![]() | Marquis, R.W. / Yamashita, D.S. / Ru, Y. / LoCastro, S.M. / Oh, H.J. / Erhard, K.F. / DesJarlais, R.L. / Head, M.S. / Smith, W.W. / Zhao, B. ...Marquis, R.W. / Yamashita, D.S. / Ru, Y. / LoCastro, S.M. / Oh, H.J. / Erhard, K.F. / DesJarlais, R.L. / Head, M.S. / Smith, W.W. / Zhao, B. / Janson, C.A. / Abdel-Meguid, S.S. / Tomaszek, T.A. / Levy, M.A. / Veber, D.F. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.5 Å |
Structure data | ![]() PDB-1au3: ![]() PDB-1au4: |
Chemicals | ![]() ChemComp-PCM: ![]() ChemComp-HOH: ![]() ChemComp-INP: |
Source |
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![]() | HYDROLASE / SULFHYDRYL PROTEINASE |