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Structure paper

TitleStructure of a cephalosporin synthase.
Journal, issue, pagesNature, Vol. 394, Page 805-809, Year 1998
Publish dateJun 5, 1998 (structure data deposition date)
AuthorsValegard, K. / van Scheltinga, A.C. / Lloyd, M.D. / Hara, T. / Ramaswamy, S. / Perrakis, A. / Thompson, A. / Lee, H.J. / Baldwin, J.E. / Schofield, C.J. ...Valegard, K. / van Scheltinga, A.C. / Lloyd, M.D. / Hara, T. / Ramaswamy, S. / Perrakis, A. / Thompson, A. / Lee, H.J. / Baldwin, J.E. / Schofield, C.J. / Hajdu, J. / Andersson, I.
External linksNature / PubMed:9723623
MethodsX-ray diffraction
Resolution1.3 - 1.5 Å
Structure data

PDB-1dcs:
DEACETOXYCEPHALOSPORIN C SYNTHASE FROM S. CLAVULIGERUS
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-1rxf:
DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II)
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1rxg:
DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) AND 2-OXOGLUTARATE
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-FE:
Unknown entry

ChemComp-AKG:
2-OXOGLUTARIC ACID

Source
  • streptomyces clavuligerus (bacteria)
KeywordsOXIDOREDUCTASE / FERROUS OXYGENASE / CEPHALOSPORIN / 2-OXOGLUTARATE / ANTIBIOTICS / MEROHEDRAL TWINNING / ANTIBIOTIC BIOSYNTHESIS

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