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TitleStructural analysis of the GAP-related domain from neurofibromin and its implications.
Journal, issue, pagesEMBO J., Vol. 17, Page 4313-4327, Year 1998
Publish dateJul 8, 1998 (structure data deposition date)
AuthorsScheffzek, K. / Ahmadian, M.R. / Wiesmuller, L. / Kabsch, W. / Stege, P. / Schmitz, F. / Wittinghofer, A.
External linksEMBO J. / PubMed:9687500
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1nf1:
THE GAP RELATED DOMAIN OF NEUROFIBROMIN
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / NEUROFIBROMIN / TYPE I NEUROFIBROMATOSIS / NF1 / RAS / GAP / SIGNAL TRANSDUCTION / CANCER / GROWTH REGULATION / GTP HYDROLYSIS / PATIENT MUTATION / ARGININE FINGER

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