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TitleInterfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
Journal, issue, pagesStructure, Vol. 6, Page 627-636, Year 1998
Publish dateMar 12, 1998 (structure data deposition date)
AuthorsXue, Y. / Bjorquist, P. / Inghardt, T. / Linschoten, M. / Musil, D. / Sjolin, L. / Deinum, J.
External linksStructure / PubMed:9634700
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-1a7c:
HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR/PEPTIDE / SERINE PROTEASE INHIBITOR / PAI-1 / CARBOHYDRATE / INHIBITOR COMPLEX / PROTEASE INHIBITOR-PEPTIDE COMPLEX / HYDROLASE INHIBITOR-PEPTIDE complex

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