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TitleCrystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 95, Page 3408-3412, Year 1998
Publish dateApr 23, 1998 (structure data deposition date)
AuthorsMaskos, K. / Fernandez-Catalan, C. / Huber, R. / Bourenkov, G.P. / Bartunik, H. / Ellestad, G.A. / Reddy, P. / Wolfson, M.F. / Rauch, C.T. / Castner, B.J. ...Maskos, K. / Fernandez-Catalan, C. / Huber, R. / Bourenkov, G.P. / Bartunik, H. / Ellestad, G.A. / Reddy, P. / Wolfson, M.F. / Rauch, C.T. / Castner, B.J. / Davis, R. / Clarke, H.R. / Petersen, M. / Fitzner, J.N. / Cerretti, D.P. / March, C.J. / Paxton, R.J. / Black, R.A. / Bode, W.
External linksProc. Natl. Acad. Sci. USA / PubMed:9520379
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1bkc:
CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-INN:
N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsZN-ENDOPEPTIDASE / HYDROLASE / TNF-ALPHA

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