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TitleCrystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases.
Journal, issue, pagesBiochemistry, Vol. 37, Page 2622-2628, Year 1998
Publish dateOct 14, 1997 (structure data deposition date)
AuthorsMaveyraud, L. / Pratt, R.F. / Samama, J.P.
External linksBiochemistry / PubMed:9485412
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1axb:
TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI INHIBITED WITH AN ACYLATION TRANSITION STATE ANALOG
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-FOS:
[[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / ANTIBIOTIC RESISTANCE / BETA-LACTAMASE

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