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Structure paper

TitleStructure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Journal, issue, pagesBiochemistry, Vol. 37, Page 971-982, Year 1998
Publish dateOct 4, 1997 (structure data deposition date)
AuthorsLu, F. / Schumacher, M.A. / Arvidson, D.N. / Haldimann, A. / Wanner, B.L. / Zalkin, H. / Brennan, R.G.
External linksBiochemistry / PubMed:9454587
MethodsX-ray diffraction
Resolution2.7 - 3 Å
Structure data

PDB-2pue:
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2puf:
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2pug:
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-ADE:
ADENINE

ChemComp-HOH:
WATER

ChemComp-GUN:
GUANINE

ChemComp-HPA:
HYPOXANTHINE

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION/DNA / COMPLEX (DNA-BINDING PROTEIN-DNA) / DNA-BINDING REGULATORY PROTEIN / EXTENDED COREPRESSOR SPECIFICITY / TRANSCRIPTION-DNA COMPLEX

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