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Structure paper

TitleStructural evidence for a second sialic acid binding site in avian influenza virus neuraminidases.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 94, Page 11808-11812, Year 1997
Publish dateAug 27, 1997 (structure data deposition date)
AuthorsVarghese, J.N. / Colman, P.M. / van Donkelaar, A. / Blick, T.J. / Sahasrabudhe, A. / McKimm-Breschkin, J.L.
External linksProc. Natl. Acad. Sci. USA / PubMed:9342319
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-1mwe:
THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • influenza a virus
KeywordsHYDROLASE / NEURAMINIDASE / AVIAN INFLUENZA / SIALIC ACID BINDING / HEMAGGLUTINATION SITE / HEME ABSORBING SITE

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