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TitleCrystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog.
Journal, issue, pagesEMBO J., Vol. 16, Page 5572-5581, Year 1997
Publish dateSep 22, 1997 (structure data deposition date)
AuthorsHubbard, S.R.
External linksEMBO J. / PubMed:9312016
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1ir3:
PHOSPHORYLATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCOMPLEX (TRANSFERASE/SUBSTRATE) / TYROSINE KINASE / SIGNAL TRANSDUCTION / PHOSPHOTRANSFERASE / COMPLEX (KINASE-PEPTIDE SUBSTRATE-ATP ANALOG) / ENZYME / COMPLEX (TRANSFERASE-SUBSTRATE) / COMPLEX (TRANSFERASE-SUBSTRATE) complex

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