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TitleSteroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Journal, issue, pagesStructure, Vol. 5, Page 799-812, Year 1997
Publish dateMar 13, 1997 (structure data deposition date)
AuthorsBennett, M.J. / Albert, R.H. / Jez, J.M. / Ma, H. / Penning, T.M. / Lewis, M.
External linksStructure / PubMed:9261071
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1afs:
RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-TES:
TESTOSTERONE / hormone*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / NAD

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