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Structure paper

TitleStructural determinants of specificity in the cysteine protease cruzain.
Journal, issue, pagesProtein Sci., Vol. 6, Page 1603-1611, Year 1997
Publish dateApr 21, 1997 (structure data deposition date)
AuthorsGillmor, S.A. / Craik, C.S. / Fletterick, R.J.
External linksPubMed:9260273
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-1aim:
CRUZAIN INHIBITED BY BENZOYL-TYROSINE-ALANINE-FLUOROMETHYLKETONE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2aim:
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ZYA:
BENZOYL-TYROSINE-ALANINE-FLUORO-METHYL KETONE

ChemComp-HOH:
WATER

ChemComp-ZRA:
BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE

Source
  • trypanosoma cruzi (eukaryote)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / CYSTEINE PROTEASE / TRYPANOSOMA CRUZI / FLUOROMETHYL KETONE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / PROTEINASE / PROTEASE

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