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-Structure paper
Title | An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex. |
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Journal, issue, pages | J. MED. CHEM., Vol. 40, Page 2440-2444, Year 1997 |
Publish date | Jan 17, 2003 (structure data deposition date) |
Authors | Smith III, A.B. / Hirschmann, R. / Pasternak, A. / Yao, W. / Sprengeler, P.A. / Holloway, M.K. / Kuo, L.C. / Chen, Z. / Darke, P.L. / Schleif, W.A. |
External links | J. MED. CHEM. / PubMed:9258349 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1npa: |
Chemicals | ChemComp-3NH: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / protease / HIV / Aspartyl protease |