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Structure paper

TitleThe Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Journal, issue, pagesScience, Vol. 277, Page 333-338, Year 1997
Publish dateJul 3, 1997 (structure data deposition date)
AuthorsScheffzek, K. / Ahmadian, M.R. / Kabsch, W. / Wiesmuller, L. / Lautwein, A. / Schmitz, F. / Wittinghofer, A.
External linksScience / PubMed:9219684
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1wq1:
RAS-RASGAP COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-AF3:
ALUMINUM FLUORIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCOMPLEX (GTP-BINDING/GTPASE ACTIVATION) / RAS / GAP / SIGNAL TRANSDUCTION / GROWTH REGULATION / GTP HYDROLYSIS / TRANSITION STATE / COMPLEX (GTP-BINDING-GTPASE ACTIVATION) / COMPLEX (GTP-BINDING-GTPASE ACTIVATION) complex

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