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TitleA combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE).
Journal, issue, pagesChem. Biol., Vol. 4, Page 149-155, Year 1997
Publish dateFeb 12, 1997 (structure data deposition date)
AuthorsRano, T.A. / Timkey, T. / Peterson, E.P. / Rotonda, J. / Nicholson, D.W. / Becker, J.W. / Chapman, K.T. / Thornberry, N.A.
External linksChem. Biol. / PubMed:9190289
MethodsX-ray diffraction
Resolution2.73 Å
Structure data

PDB-1ibc:
CRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME
Method: X-RAY DIFFRACTION / Resolution: 2.73 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / PROTEASE / CYSTEINE PROTEASE / INTERLEUKIN-1BETA CONVERTING ENZYME / ICE / CASPASE-1 / HYDROLASE-HYDROLASE INHIBITOR complex

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