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TitleThree-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
Journal, issue, pagesJ. Mol. Biol., Vol. 267, Page 1207-1222, Year 1997
Publish dateDec 27, 1996 (structure data deposition date)
AuthorsLescar, J. / Stouracova, R. / Riottot, M.M. / Chitarra, V. / Brynda, J. / Fabry, M. / Horejsi, M. / Sedlacek, J. / Bentley, G.A.
External linksJ. Mol. Biol. / PubMed:9150407
MethodsX-ray diffraction
Resolution2.2 - 2.6 Å
Structure data

PDB-1mf2:
ANTI HIV1 PROTEASE FAB COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2hrp:
ANTIGEN-ANTIBODY COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNOGLOBULIN / FAB FRAGMENT / CROSS-REACTIVITY / HIV1 PROTEASE / ENZYME INHIBITION / COMPLEX (IMMUNOGLOBULIN/PEPTIDE) / COMPLEX (IMMUNOGLOBULIN-PEPTIDE) / COMPLEX (IMMUNOGLOBULIN-PEPTIDE) complex

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