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Structure paper

TitleThe role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
Journal, issue, pagesJ. Mol. Biol., Vol. 266, Page 847-856, Year 1997
Publish dateDec 15, 1996 (structure data deposition date)
AuthorsSchweins, T. / Scheffzek, K. / Assheuer, R. / Wittinghofer, A.
External linksJ. Mol. Biol. / PubMed:9102473
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1jah:
H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MAGNESIUM
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1jai:
H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GCP:
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER / GMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsGTP-BINDING / GTP HYDROLYSIS / SIGNAL TRANSDUCTION / CANCER / G-DOMAIN

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