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-Structure paper
Title | Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones. |
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Journal, issue, pages | J. Med. Chem., Vol. 40, Page 1149-1164, Year 1997 |
Publish date | Dec 10, 1996 (structure data deposition date) |
Authors | Skulnick, H.I. / Johnson, P.D. / Aristoff, P.A. / Morris, J.K. / Lovasz, K.D. / Howe, W.J. / Watenpaugh, K.D. / Janakiraman, M.N. / Anderson, D.J. / Reischer, R.J. ...Skulnick, H.I. / Johnson, P.D. / Aristoff, P.A. / Morris, J.K. / Lovasz, K.D. / Howe, W.J. / Watenpaugh, K.D. / Janakiraman, M.N. / Anderson, D.J. / Reischer, R.J. / Schwartz, T.M. / Banitt, L.S. / Tomich, P.K. / Lynn, J.C. / Horng, M.M. / Chong, K.T. / Hinshaw, R.R. / Dolak, L.A. / Seest, E.P. / Schwende, F.J. / Rush, B.D. / Howard, G.M. / Toth, L.N. / Wilkinson, K.R. / Kakuk, T.J. / Johnson, C.W. / Cole, S.L. / Zaya, R.M. / Zipp, G.L. / Possert, P.L. / Dalga, R.J. / Zhong, W.-Z. / Williams, M.G. / Romines, K.R. |
External links | J. Med. Chem. / PubMed:9089336 |
Methods | X-ray diffraction |
Resolution | 2 - 2.5 Å |
Structure data | PDB-1hpo: PDB-7upj: |
Chemicals | ChemComp-UNI: ChemComp-HOH: ChemComp-INU: |
Source |
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Keywords | HYDROLASE / ACID PROTEASE / ASPARTYL PROTEASE |