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Structure paper

TitleStructural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Journal, issue, pagesBiochemistry, Vol. 36, Page 1704-1718, Year 1997
Publish dateAug 24, 1996 (structure data deposition date)
AuthorsEssen, L.O. / Perisic, O. / Katan, M. / Wu, Y. / Roberts, M.F. / Williams, R.L.
External linksBiochemistry / PubMed:9048554
MethodsX-ray diffraction
Resolution2.3 - 2.95 Å
Structure data

PDB-1djw:
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHONATE
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-1djx:
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-1,4,5-TRISPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1djy:
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2,4,5-TRISPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1djz:
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-4,5-BISPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-CIP:
INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-I3P:
D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE

ChemComp-I2P:
D-MYO-INOSITOL-2,4,5-TRIPHOSPHATE

ChemComp-IP2:
D-MYO-INOSITOL-4,5-BISPHOSPHATE

Source
  • rattus norvegicus (Norway rat)
KeywordsLIPID DEGRADATION / PHOSPHORIC DIESTER HYDROLASE / HYDROLASE / TRANSDUCER / CALCIUM-BINDING / PHOSPHOLIPASE C / PHOSPHOINOSITIDE-SPECIFIC

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