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TitleStructure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase.
Journal, issue, pagesJ. Mol. Biol., Vol. 266, Page 381-399, Year 1997
Publish dateJul 8, 1996 (structure data deposition date)
AuthorsLawrence, M.C. / Barbosa, J.A.R.G. / Smith, B.J. / Hall, N.E. / Pilling, P.A. / Ooi, H.C. / Marcuccio, S.M.
External linksJ. Mol. Biol. / PubMed:9047371
MethodsX-ray diffraction
Resolution2.45 - 2.6 Å
Structure data

PDB-1fdy:
N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH HYDROXYPYRUVATE
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-1fdz:
N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH PYRUVATE VIA BOROHYDRIDE REDUCTION
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-3PY:
3-HYDROXYPYRUVIC ACID

ChemComp-HOH:
WATER

ChemComp-PYR:
PYRUVIC ACID

Source
  • escherichia coli (E. coli)
KeywordsLYASE / ALDOLASE / OXO-ACID LYASE / ALPHA-KETO-ACID LYASE / CARBON-CARBON LYASE

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