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-Structure paper
Title | Crystal structure of human cathepsin K complexed with a potent inhibitor. |
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Journal, issue, pages | Nat. Struct. Biol., Vol. 4, Page 105-109, Year 1997 |
Publish date | Jan 8, 1997 (structure data deposition date) |
Authors | McGrath, M.E. / Klaus, J.L. / Barnes, M.G. / Bromme, D. |
External links | Nat. Struct. Biol. / PubMed:9033587 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-1mem: |
Chemicals | ChemComp-0D6: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / OSTEOPOROSIS / PROTEASE / DRUG DESIGN / CYSTEINE / OSTEOCLAST / Disease mutation / Disulfide bond / Glycoprotein / Lysosome / Thiol protease / Zymogen / HYDROLASE-HYDROLASE INHIBITOR complex |