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TitleStrategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5 A resolution.
Journal, issue, pagesProtein Sci., Vol. 5, Page 2453-2458, Year 1996
Publish dateMay 27, 2003 (structure data deposition date)
AuthorsSaxena, A.K. / Singh, T.P. / Peters, K. / Fittkau, S. / Betzel, C.
External linksProtein Sci. / PubMed:8976553
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1pfg:
Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • engyodontium album (fungus)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Proteinase K / octapeptide / inhibitor / complex / hydrolase / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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